‘The Dr. Miles Medical Company was founded in Indiana, in 1884 by Franklin Miles, a specialist in the treatment of eye and ear disorders, with an interest in the connection of the nervous system to overall health. By 1890, the sales success of his patent medicine tonic, Dr. Miles’ Nervine, in treating “nervous” ailments (including “nervousness or nervous exhaustion,sleeplessness, hysteria, headache, neuralgia, backache, pain, epilepsy, spasms, fits, and St. Vitus’ dance”) led him to develop a mail order medicine business. Nervine remained on the market as a “calmative” until the late 1960s.”

- Wikipedia